Influence of endoscopic submucosal dissection on esophageal motility

Table 1 Clinicopathological features and esophageal manometry of 12 patients with esophageal epithelial neoplasms treated by endoscopic submucosal dissection

Number of patient	Sex	Age (yr)	Post-ESD pathology	Circumferential extension	Grade of dysphagia	Pressure of esophageal body (mmHg)			Non-peristaltic contractions of esophageal body in ten water swallows
						7.0 cm above LES	3.0 cm above LES	mean
1	F	64	T1 cancer	2/4-3/4	0	129.8	108.7	119.2	0%
2	M	64	LGIN	1/4-2/4	0	99.9	75.3	87.6	0%
3	M	53	HGIN	2/4-3/4	2	26.1	45.2	35.6	40%
4	F	55	HGIN	2/4-3/4	Sporadic	31.8	41.2	36.5	50%
5	M	55	HGIN/Tis	1/4-2/4	0	139.1	125.9	132.5	0%
6	M	55	LGIN	2/4-3/4	Sporadic	90.1	31.9	61.0	20%
7	M	58	T1 cancer	> 3/4	Sporadic	34.1	21.7	27.9	20%
8	F	64	HGIN/Tis	1/4-2/4	0	58.6	76.6	67.6	0%
9	F	55	LGIN	1/4-2/4	0	99.0	109.2	104.1	0%
10	F	57	HGIN	> 3/4	1	34.3	52.5	43.4	50%
11	F	58	HGIN	1/4-2/4	0	96.2	109.2	102.7	0%
12	M	57	LGIN	1/4-2/4	0	90.6	76.2	83.4	0%

HGIN: High grade intraepithelial neoplasia; LGIN: Low grade intraepithelial neoplasia; LES: Lower esophageal sphincter; ESD: Endoscopic submucosal dissection; Tis: Cancer in situ; M: Male; F: Female.