Original Article
Copyright ©2012 Baishideng Publishing Group Co.
World J Gastroenterol. May 14, 2012; 18(18): 2188-2196
Published online May 14, 2012. doi: 10.3748/wjg.v18.i18.2188
Figure 2
Figure 2 Histological appearance of the gastric mucosa of HE stained sections of the studied groups. A: Sham-operated showing intact mucosa; B: Gastric ischemia reperfusion (I/R) showing hemorrhages, edema and ulceration; C: Agmatine (AGM) treated group (100 mg/kg, i.p. prior to I/R) with marked preservation of gastric mucosa and disappearance of ulceration and hemorrhages; D: Effect of inhibition of Akt/phosphatidyl inositol-3-kinase (PI3K) (wortmannin 15 μg/kg, i.p.) prior to AGM treatment, showing extensive lesions and salvage of gastric mucosa into the lumen (× 20 magnification).