Serum leptin and ghrelin in chronic hepatitis C patients with steatosis

Table 3 Leptin and ghrelin concentrations at baseline and end of follow-up in patients infected with hepatitis C virus genotypes-1 and -3 by response to therapy, as well as mixed effect model derived estimates of differences in mean scores (mean ± SD)

Variable	Responders	Non-responders	P-value for the adjusted difference1
Leptin
Baseline (ng/mL)	30.99 (9.185)	38.43 (11.58)	NS
End of Follow-up (ng/mL)	23.76 (8.055)	34.10 (11.53)	0.01
Ghrelin
Baseline (ng/mL)	0.532 (0.410)	0.377 (0.223)	0.01
End of Follow-up (ng/mL)	0.438 (0.288)	0.345 (0.237)	0.05

¹Adjusted for both leptin and ghrelin concentrations. NS: Non-significant.