Lipopolysaccharide induces and activates the Nalp3 inflammasome in the liver

doi:10.3748/wjg.v17.i43.4772

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Nov 21, 2011 (publication date) through Apr 26, 2024

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Times Cited (99)

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 21, 2011; 17(43): 4772-4778
Published online Nov 21, 2011. doi: 10.3748/wjg.v17.i43.4772

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Figure 1 Lipopolysaccharide stimulation results in liver damage. C57BL/6 wild-type chow-fed mice (three per group) were injected intraperitoneally with lipopolysaccharide (LPS) for 2, 4, 6, 18 or 24 h. Serum was separated from whole blood and analyzed for alanine aminotransferase (ALT), which was significantly increased after 4 h of LPS stimulation. Mean ± SD are shown. ^aP < 0.01.

Citation: Ganz M, Csak T, Nath B, Szabo G. Lipopolysaccharide induces and activates the Nalp3 inflammasome in the liver. World J Gastroenterol 2011; 17(43): 4772-4778
URL: https://www.wjgnet.com/1007-9327/full/v17/i43/4772.htm
DOI: https://dx.doi.org/10.3748/wjg.v17.i43.4772