Brief Article
Copyright ©2010 Baishideng Publishing Group Co.
World J Gastroenterol. Dec 14, 2010; 16(46): 5852-5860
Published online Dec 14, 2010. doi: 10.3748/wjg.v16.i46.5852
Figure 4
Figure 4 Effect of the blockade of the BKCa channel with iberiotoxin (10-7 mol/L) of lower esophageal sphincter (A) circular (n = 6-8) and (B) sling (n = 7-11) smooth muscle tone with intact nerves or blocked with tetrodotoxin (10-6 mol/L). A: For the circular muscle, tetrodotoxin (TTX) or iberiotoxin (IbTX) did not significantly change the resting tension (P > 0.05). The combined blockade of the nerves and the BKCa channel also resulted in no significant change of the overall muscle tone (P > 0.05); B: Similarly, for the sling muscle, TTX, IbTX or TTX and IbTX together did not significantly modulate the basal resting tone (P > 0.05). //: Separates different experiments.