Meta-analysis of probiotics for the treatment of irritable bowel syndrome

Table 7 Recommendations for future research studies examining probiotics as a treatment for irritable bowel syndrome

Recommendations
More trials testing the same probiotic strain
Larger sample size
Longer duration of treatment and follow-up
Intention to treat analysis:
All participants analyzed with the group to which they were originally assigned, regardless of compliance with treatment, response to treatment, or use of prohibited (non-study) medications.
Greater efforts to minimize loss to follow-up
Standardized assessment of IBS outcomes
Provide some assessment of global relief of IBS symptoms
Detailed collection and reporting of data on potential adverse reactions