Liver Cancer
Copyright ©2007 Baishideng Publishing Group Co.
World J Gastroenterol. Oct 28, 2007; 13(40): 5299-5305
Published online Oct 28, 2007. doi: 10.3748/wjg.v13.i40.5299
Figure 1
Figure 1 Silibinin's effects on growth of human hepatoma cells. A: MTT assay showed silibinin's dose dependent anti-proliferative effects on HuH7 cells. A significant decrease in proliferation compared to control was noted from silibinin ≥ 180 μmol/L. The IC25 is determined to be 120 μmol/L and the IC50 is determined to be 240 μmol/L; B: Silibinin's effects on other human HCC cell growth. PLC/PRF/5, HepG2, and Hep3B HCC cells were treated with silibinin at IC25 and IC50 doses for HuH7 cells. Silibinin significantly reduced growth of all three HCC cells in different rates. aP < 0.05 vs control.