Neutrophil depletion-but not prevention of Kupffer cell activation-decreases the severity of cerulein-induced acute pancreatitis

Table 3 IL-6 and IL-10 concentrations in serum, pancreas, lungs, and livers in control (CONT) mice and mice treated with cerulein (CER)

	CONT	CER
Serum IL-6 (pg/mL)	8.9 [8.7 - 11.4]	267.5 [98.0 - 312.0]	P = 0.02
Serum Il-10 (pg/mL)	11.8 [8.9 - 14.7]	18.7 [10.9 - 21.6]	P = 0.23
Pancreatic IL-6 (pg/mg protein)	1.2 [0.5 - 1.9]	8.4 [6.4 - 13.2]	P = 0.02
Pancreatic IL-10 (pg/mg protein)	0.08 [0.03 - 0.20]	0.32 [0.20 - 0.79]	P = 0.03
Pulmonary IL-6 (pg/mg protein)	1.5 [0.5 - 2.1]	3.0 [2.4 - 6.9]	P = 0.004
Pulmonary IL-10 (pg/mg protein)	0.10 [0.01 - 0.20]	0.87 [0.42 - 3.80]	P = 0.06
Hepatic IL-6 (pg/mg protein)	1.15 [0.80 - 1.60]	8.20 [5.60 - 11.52]	P = 0.006
Hepatic IL-10 (pg/mg protein)	0.12 [0.05 - 0.20]	0.43 [0.33 - 0.48]	P = 0.06

n ≥ 5 in each group. Data in CER and CONT groups were compared by Mann-Whitney test.