Fatty liver in H63D homozygotes with hyperferritinemia

Table 1 Clinical, biochemical and serological features of the four H63D homozygous patients

	Case 1	Case 2	Case 3	Case 4
Age (yr)	36	35	44	66
BMI (kg/m2)	30	24	32.5	31
Blood pressure (mmHg)	140/100	130/80	160/100	150/95
Alcohol intake (g/wk)	8	0	60	0
Blood sugar (mmol/L)	4.2	4.6	5.6	9.5
Total cholesterol (mmol/L)	4.1	4.3	5.5	6
Triglicerides (mmol/L)	1.6	1.5	3.6	2.9
AST (U/L)	46	69	44	15
ALT (U/L)	117	175	112	18
γGT (U/L)	50	45	70	30
Ferritin (µg/L)	454	350	568	423
HCV/HBV serology	neg	neg	neg	neg

Legend: BMI=body mass index; wk=week; neg=negative. Normal ranges: BMI 18 - 25 kg/m²; blood pressure max < 120mmHg, min<80mmHg (see the seventh report of the Joint National Committee on high blood pressure, NIH publication no 03 - 5233, December 2003); blood sugar < 6mmol/L.