Gastric Cancer
Copyright ©The Author(s) 2003.
World J Gastroenterol. Sep 15, 2003; 9(9): 1909-1914
Published online Sep 15, 2003. doi: 10.3748/wjg.v9.i9.1909
Figure 1
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Figure 1 Effect of c9,t11-CLA on invasion of SGC-7901 cells detected by reconstituted basement membrane invasion assay (100 ×). A: There are more invading SGC-7901 cells in the nega-tive control group. B: There are less invading SGC-7901 cells in the 200 μmol/L c9,t11-CLA group.
Figure 2
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Figure 2 Effect of c9,t11-CLA on chemotaxic migration of SGC-7901 cells detected by chemotaxied-motion assay (100 ×). A: There are more invading SGC-7901 cells in the negative con-trol group. B: There are less invading SGC-7901 cells in the 200 μmol/L c9,t11-CLA group.
Figure 3
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Figure 3 Effect of c9,t11-CLA on the attachment ability of SGC-7901 cells.
Figure 4
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Figure 4 Effects of c9,t11-CLA on Gelatinase secretion in SGC-7901 cells detected by zymography. A, B, C, D are 200 μmol/L, 100 μmol/L, 50 μmol/L, 25 μmol/L c9,t11-CLA, respectively. E is the negative control group.
Figure 5
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Figure 5 Quantitation of 92 and 72 kDa type IV Collagenase levels in SGC-7901 cells by ChemiImager 4000. A, B, C, D are 200 μmol/L, 100 μmol/L, 50 μmol/L, 25 μmol/L c9,t11-CLA, respectively. E is the negative control group.
Figure 6
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Figure 6 Effects of c9,t11-CLA on expression of TIMP-1 mRNA and TIMP-2 mRNA in SGC-7901 cells detected by RT-PCR. Top: Expression of TIMP-1 mRNA. Middle: Expression of TIMP-2 mRNA. A, B, C, D are 20 μmol/L, 100 μmol/L, 50 μmol/L, 25 μmol/L c9,t11-CLA, respectively. E is the negative control group.
Figure 7
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Figure 7 Quantitation of TIMP-1 and TIMP-2 mRNA levels in the SGC-7901 cells by ChemiImager 4000. A, B, C, D are 200 μmol/L, 100 μmol/L, 50 μmol/L, 25 μmol/L c9,t11-CLA, respectively. E is the negative control group.