Clinical Research
Copyright ©The Author(s) 2002.
World J Gastroenterol. Jun 15, 2002; 8(3): 562-566
Published online Jun 15, 2002. doi: 10.3748/wjg.v8.i3.562
Figure 1
Figure 1 Contour plots of cytokine expression in CD14+ cells. These contour plots show representative experiments for the detection of spontaneous expression (buffer control, left column) and HCV NS5b-induced expression (1 μg/mL, right column) of IL-1β (a), IL-10 (b), IL-12 (c) and TNF-((d) in peripheral blood CD14+ monocytes of patient # 23 with chronic hepatitis C at 12 hours of incubation.
Figure 2
Figure 2 Induction of cytokines by the HCV NS4 protein. The graph displays the fractions of IL-1β (a), IL-10 (b), IL-12 (c) and TNF-((d) producing monocytes 12 hours after stimulation with recombinant NS4 protein (1 μg/mL) for patients with chronic hepatitis C (filled squares), aviremic anti-HCV seropositives (upward triangles), and non-HCV related controls (downward triangles). Each dot represents the mean percentage of a single patient obtained from triplicate experiments. The horizontal bar gives the mean of each group.