SF/HGF-c-Met autocrine and paracrine promote metastasis of hepatocellular carcinoma

Figure 1 SF/HGF and c-met expression in HCC cell lines. A: c-met transcription; B: SF/HGF transcription 1: Mark; 2: MHCC-1; 3: HepG2; 4: Hep3B; 5: SMMC7721; 6: pBS7.3; C: c-met protein expression; D: SF/HGF protein expression (1: Mark; 2: SMMC7721; 3: Hep3B; 4: HepG2; 5: MHCC-1).

Figure 2 A: cell morphology comparison. × 400. Left: SMMC7721; Right: SF7721; Up: Control at “0” time ; Left down: SMMC7721 at 16 h after wound healing; Right down: SF7721 at 16 h after wound helaing; B: Cell morphology comparison × 400; C: Cell growth curve before and after gene transfection.

Figure 3 C-met inhibition assay.