Bile acid formation in primary human hepatocytes

Figure 1 Distribution of cholic acid, chenodeoxycholic acid and precursors formed in primary cultures of human hepatocytes.

Figure 2 Formation of cholic acid and chenodeoxycholic acid in primary cultures of human hepatocytes during d 2, 4, 6 and 8. Effects of adding T3 and dexa methasone (DEX) alone and in combination.

Figure 3 Distribution of cholic acid, chenodeoxycholic acid and precursors formed in cultures of HepG2 cells (data from ref. 7).

Figure 4 Conjugation of bile acids and precursors formed in primary cultures of human hepatocytes.

Figure 5 Distribution of free and conjugated bile acids and potential interme diates isolated from medium on the fifth day of incubating primary human hepatoc ytes. CDCA = chenodeoxycholic acid; CA = cholic acid.

Figure 6 Conjugation of bile acids and precursors formed in cultures of HepG2 cells (data from ref. 7).

Figure 7 Effect of cyclosporin A on bile acid formation in primary human hepa tocytes.