Disease trends after Helicobacter pylori eradication based on Japanese nationwide claims and the health check-up database

Figure 1 Number of patients who received primary Helicobacter pylori eradication therapy, by sex and age group at the time of eradication.

Figure 2 Incidence of gastroesophageal reflux disease in the 3-year period before the year of eradication and after the year of eradication. A: By age categories; B: By calendar year and month.

Figure 3 Incidence of Barrett’s esophagus in the 3-year period before the year of eradication and after the year of eradication. A: By age category; B: By calendar year and month.

Figure 4 Incidence of inflammatory bowel disease in the 3-year period before the year of eradication and after the year of eradication by age category. A: Crohn’s disease; B: Ulcerative colitis.

Figure 5 Prevalence of allergic diseases in the 3-year period before the year of eradication and after the year of eradication. A: By age category; B: By calendar year and month.

Figure 6 Change in the average body mass index and percentage of patient with metabolic syndrome before and after the year of eradication. A: Average body mass index; B: Percentage of patients with metabolic syndrome. Year 0 is the year of primary eradication, and negative values represent years before primary eradication. BMI: Body mass index.