Natural history and outcomes of patients with liver cirrhosis complicated by hepatic hydrothorax

Figure 1 Kaplan-Meier survival curves. Kaplan-Meier survival curves showing transplant-free survival at 12 mo, with liver transplantation and death treated as composite endpoints, and overall patient survival at 12 mo, with patients censored at the time of liver transplantation (ticks on survival curve).

Figure 2 Multivariate survival analysis. A: Multivariable Cox regression of overall patient survival (censored for transplantation), showing survival estimates for patients with hepatic hydrothorax by smoking and acute kidney injury status, with age and model for end-stage liver disease (MELD) scores held at the mean values; B: Bootstrapped pointwise confidence intervals for survival functions by active smoking status, in the absence of acute kidney injury and with age and MELD held at the means, demonstrating a robust association between active smoking and mortality in patients with hepatic hydrothorax. AKI: Acute kidney injury.