Pituitary stalk interruption syndrome and liver changes: From clinical features to mechanisms

Figure 1 The liver tissue is divided into nodules by fibrous septa of different widths. Most of the hepatocytes in the nodules appear as bullous steatosis.

Figure 2 Edema of hepatocytes around the fibrous septum, a few of which showed balloon-like changes, and Mallory body can be seen. A: Hematoxylin-eosin staining (HE), 200 ×; B: HE, 400 ×.

Figure 3 Cranial magnetic resonance: abnormal pituitary.

Figure 4 The mechanisms of nonalcoholic fatty liver disease induced by hormone deficiency. IGF-1: Insulin-like growth factor-1; IL-6: Interleukin-6; NAFLD: Nonalcoholic fatty liver disease; PRL: Prolactin; GH: Growth hormone; STAT: Signal transducer and activator of transcription; TH: Thyroid hormone.