Multifocal gastrointestinal epithelioid angiosarcomas diagnosed by endoscopic mucosal resection: A case report

Figure 1 Endoscopy. A: Gastroscopy revealed a 0.5 cm × 0.6 cm centrally ulcerated polypoid lesion in the gastric body; B: A 0.8 cm × 0.8 cm polypoid lesion in the ascending colon; C: A 1.2 cm × 1.0 cm hyperaemic mass in the transverse colon; and D: A 0.8 cm × 0.8 cm polypoid nodule with hemorrhagic tendency and blood clots in the sigmoid colon.

Figure 2 Histopathological findings. Poorly differentiated neoplasms consisting of large cells with pleomorphic nuclei and abundant eosinophilic cytoplasm were observed. A: Haematoxylin and eosin (HE) staining section × 40; B: HE staining section (× 100); C: HE staining section (× 200); and D: HE staining section (× 400).

Figure 3 Immunohistochemical staining. A: Immunostaining for CD31; B: Immunostaining for CD34; and C: Immunostaining for pan-cytokeratin.

Figure 4 Whole-body maximum intensity projection 18F- fluorodeoxyglucose and positron emission tomography image. A: Remarkably increased fluorodeoxyglucose metabolism in the colon and mediastinal lymph nodes, as well as the right humerus; B: Positron emission tomography; C: Computed tomography; and D: Positron emission tomography/computed tomography in axial projection showed multiple tubular hypermetabolic lesions in the colon.