Risk of gastrointestinal cancer in a symptomatic cohort after a complete colonoscopy: Role of faecal immunochemical test

Figure 1 Study population flowchart. CRC: Colorectal cancer; FIT: Faecal immunochemical test; GIC: Gastrointestinal cancer.

Figure 2 Cumulative risk of gastrointestinal cancer and related death. Cumulative risk of gastrointestinal cancer and related death during the first four years after baseline evaluation according to faecal haemoglobin concentration and adjusted by sex, age and presence of significant colonic lesion. The figure is calculated with a Cox’s multivariate regression.

Figure 3 Time (mo) until gastrointestinal cancer diagnosis according to location, diagnostic test and faecal immunochemical test result. f-Hb: Faecal haemoglobin (µg Hb/g of faeces).

Figure 4 Correlation between faecal haemoglobin concentration and time to gastrointestinal cancer detection and gastrointestinal cancer-related death. GIC: Gastrointestinal cancer; r: Spearman correlation coefficient.

Figure 5 Gastrointestinal cancer diagnosis during follow up based on faecal immunochemical test result and significant colonic lesion in the basal colonoscopy. CRC: Colorectal cancer; FIT: Faecal immunochemical test; GITN: Gastrointestinal tract neoplasm; SCL: Significant colonic lesion.

Figure 6 Minimum diagnostic yield of an upper endoscopy performed at the time of faecal immunochemical test for haemoglobin determination. A: All subjects; B: subjects aged 50 years old and older. FIT: Faecal immunochemical test for haemoglobin; SCL: Significant colonic lesion; P: Differences were analysed with the Chi-square statistics.