Pathological response measured using virtual microscopic slides for gastric cancer patients who underwent neoadjuvant chemotherapy

Figure 1 An example of a virtual microscopic slide and pathological diagnosis of the residual tumor area and primary tumorous bed. The areas enclosed by a red line and a black line are the residual tumor area and the primary tumorous bed, respectively. Their square measures were automatically calculated by the software of the virtual microscopic system.

Figure 2 Survival curves of responders and non-responders classified according to pathological response of 10% cut-off evaluated using virtual microscopic slides. A: Relapse-free survival; B: Overall survival. HR: Hazard ratio; CI: Confidence interval; NR: Not reached; RFS: Relapse-free survival; OS: Overall survival.

Figure 3 Subgroup analyses of survival of responders and non-responders classified according to pathological response of 10% cut-off evaluated using virtual microscopic slides. A: Macroscopic type 4; B: Non-type 4; C: Histologically differentiated; D: Undifferentiated. OS: Overall survival; HR: Hazard ratio; CI: Confidence interval; NR: Not reached.