Analysis of the autophagy gene expression profile of pancreatic cancer based on autophagy-related protein microtubule-associated protein 1A/1B-light chain 3

Figure 1 Box diagram of the gene expression distribution. A: Box diagram of the gene expression distribution of each sample after the standardization of set GSE16515. B: Box diagram of the gene expression distribution of each sample after the standardization of set GSE15471.

Figure 2 Distribution diagram of the statistical analysis of gene expression. A: Distribution diagram of the statistical analysis of gene expression after the extraction of differentially expressed genes in set GSE16515; B: Distribution diagram of the statistical analysis of gene expression after the extraction of differentially expressed genes in set GSE15471. Yellow for differentially expressed genes and black for non-differentially expressed genes.

Figure 3 Distribution of the numbers of differentially expressed genes in functional items associated with apoptosis/autophagy.

Figure 4 Protein interaction network composed of differentially expressed genes.

Figure 5 Network diagram. A: Network diagram of genes that directly interact with the autophagy-related protein microtubule-associated protein 1A/1B-light chain 3 (LC3) gene; B: Network diagram of functional modules in which the LC3 gene is involved.

Figure 6 Module pairs with significant crosstalk.

Figure 7 Crosstalk relationship between modules 33 and 44.

Figure 8 The ubiquitin C gene (pivot) and its connecting modules.