Stomach wall structure and vessels imaging by acoustic resolution photoacoustic microscopy

Figure 1 Schematic of the acoustic resolution photoacoustic microscopy system (A) and photograph of the photoacoustic probe (B). P/R: Pulser/receiver; A: Preamplifier; T: Transducer, PC: Personal computer.

Figure 2 Photoacoustic image of a hair with a diameter of 80 μm. A: B-scan imaging. B: C-scan imaging.

Figure 3 Imaging of layer-by-layer structure of stomach wall.

Figure 4 Compared photoacoustic image with pathological photograph stained by hematoxylin-eosin staining for mucosa and submucosa of the tissue.

Figure 5 Photograph of the dissected stomach wall after imaging by photoacoustic microscopy (A) and photoacoustic imaging under surface of the tissue of 500 μm (red arrow indicate vessels) (B).

Figure 6 Photoacoustic imaging with laser wavelength of 700 nm for contrast agent with concentration of 12. 9 μM/mL in depth of 400 μm (A) and 2400 μm (B).