Eubiotic properties of rifaximin: Disruption of the traditional concepts in gut microbiota modulation

doi:10.3748/wjg.v23.i25.4491

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 7, 2017; 23(25): 4491-4499
Published online Jul 7, 2017. doi: 10.3748/wjg.v23.i25.4491

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Figure 1 Effects of antibiotics on the gut microbiota. Systemic antibiotics are mainly used to treat extra-intestinal infections but they indirectly affect the gut microbiota composition. Rifaximin is a poorly absorbed antibiotic, exerting its action exclusively in the gastrointestinal tract. In addition to the expected antimicrobial properties, rifaximin inhibits bacterial virulence, down-regulates inflammatory response and has the potential to positively modulate the composition of gut microbial community.

Citation: Ponziani FR, Zocco MA, D’Aversa F, Pompili M, Gasbarrini A. Eubiotic properties of rifaximin: Disruption of the traditional concepts in gut microbiota modulation. World J Gastroenterol 2017; 23(25): 4491-4499
URL: https://www.wjgnet.com/1007-9327/full/v23/i25/4491.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i25.4491