Diagnostic value evaluation of trefoil factors family 3 for the early detection of colorectal cancer

Figure 1 Comparisons of serum trefoil factor family 3 levels in colorectal cancer, colorectal adenoma, and healthy control groups. CRC: Colorectal cancer; CA: Colorectal adenoma; HC: Healthy control groups.

Figure 2 Analysis the Trefoil factors family and carcino-embryonic antigen diagnostic evaluation for discriminating the healthy control and colorectal cancer groups by receiver operating characteristic method in the training group. A: ROC of TFF3 for discriminating HC and CC; B: ROC of TFF3 for discriminating HC and early stage CC; C: ROC of TFF3 for discriminating HC and advanced stage CC; D: ROC of CEA for discriminating HC and CC; E: ROC of CEA for discriminating HC and early stage CC; F: ROC of CEA for discriminating HC and advanced stage CC; G: ROC of multivariate model for discriminating HC and CC; H: ROC of multivariate model for discriminating HC and early stage CC; I: ROC of multivariate model for discriminating HC and advanced stage CC. TFF3: Trefoil factors family; ROC: Receiver operating characteristic; HC: Healthy control; CC: Colorectal cancer.

Figure 3 Analysis the multivariate model diagnostic evaluation by receiver operating characteristic method in the validation group. A: ROC of multivariate model for discriminating HC and CC; B: ROC of multivariate model for discriminating HC and early stage CC; C: ROC of multivariate model for discriminating HC and advanced stage CC; D: ROC of multivariate model for discriminating CA and CC; E: ROC of multivariate model for discriminating CA and early stage CC; F: ROC of multivariate model for discriminating CA and advanced stage CC. TFF3: Trefoil factors family; ROC: Receiver operating characteristic; CA: Colorectal adenoma; CC: Colorectal cancer.