Chymase inhibitor TY-51469 in therapy of inflammatory bowel disease

Figure 1 Changes of factors in the experiment, model and control groups. A, B: CD4⁺CD25⁺ Tregs were detected in rat peripheral blood mononuclear cells by flow cytometry. The proportions of CD4⁺CD25⁺ Tregs are shown; C: Serum levels of IL-10, TGF-β1 and IL-17A; D: Foxp3 protein expression in colon tissues; GAPDH was used as an internal control. Each group had five rats and the pictures shown were representative of three independent experiments. IL: Interleukin; TGF: Transforming growth factor.

Figure 2 Immunohistochemistry staining results in colon tissues from different groups. IL: Interleukin; TGF: Transforming growth factor.