MicroRNA-21 promotes phosphatase gene and protein kinase B/phosphatidylinositol 3-kinase expression in colorectal cancer

Figure 1 Expression of miR-21 in colorectal cancer cell lines (n = 3).

Figure 2 Expression of PTEN protein in colorectal cancer cell lines. A: Western blot assay; B: the expression of PTEN in colorectal cancer cell lines (n = 3).

Figure 3 Changes in cell invasion ability after transfection (^aP < 0. 05, n = 3). IG: Inhibition group; NC: Negative control; BC: Blank control.

Figure 4 Effect of the miR-21 inhibitor on miR-21 expression in HCT116 cells (^aP < 0. 05, n = 3). IG: Inhibition group; NC: Negative control; BC: Blank control.

Figure 5 Effect of the miR-21 inhibitor on PTEN mRNA (A) and protein (B) expression in HCT116 cells (^aP < 0. 05, n = 3). IG: Inhibition group; NC: Negative control; BC: Blank control.

Figure 6 Protein expression of PTEN/AKT/PI3K in colorectal cancer HCT116 cell lines. A: Western blot assay; B: Protein expression in HCT116 cell lines (^aP < 0.05, n = 3). IG: Inhibition group; NC: Negative control; BC: Blank control.