Successful treatment of conversion chemotherapy for initially unresectable synchronous colorectal liver metastasis

Figure 1 Enhanced computed tomography. A, B: Before chemotherapy. A huge synchronous colorectal liver metastasis was involving the right hepatic vein (RHV; arrow) and the inferior vena cava (IVC; arrowhead); C, D: After chemotherapy. The tumor was dramatically reduced, and the IVC was isolated from the tumor (arrowhead).

Figure 2 Serum levels of carcinoembryonic antigen. FOLFOX: 5-fluorouracil, leucovorin, and oxaliplatin; Cet: Cetuximab; PTPE: Percutaneous transhepatic portal vein embolization.

Figure 3 Resected specimen. A: Cut surface. The tumor was 70 mm × 40 mm in size. The tumor was grayish-white and stony hard; B, C: Hematoxylin and eosin (HE) staining of the resected specimen; B: HE staining, × 400. Adenocarcinoma; C: HE, × 100. Approximately 50% of the adenocarcinoma was necrotic.