Moxibustion combined with acupuncture increases tight junction protein expression in Crohn&rsquo;s disease patients

doi:10.3748/wjg.v21.i16.4986

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 28, 2015; 21(16): 4986-4996
Published online Apr 28, 2015. doi: 10.3748/wjg.v21.i16.4986

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Figure 1 Morphological observation of patient intestinal mucosa tissue from two groups before and after treatment. A: HMA group before treatment; B: HMA group after treatment; C: MESA group before treatment; D: MESA group after treatment. Magnification × 200 (A-D). HMA: Herb-partitioned moxibustion combined with acupuncture group; MESA: Mesalazine group.

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Figure 2 Ultrastructural observation of patient intestinal mucosa tissue from two groups before and after treatment. A: HMA group before treatment; B: HMA group after treatment; C: MESA group before treatment; D: MESA group after treatment. Magnification × 10000 (A-D). HMA: Herb-partitioned moxibustion combined with acupuncture group; MESA: Mesalazine group.

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Figure 3 Expression of protein zonula occludens-1, occludin and claudin-1 in two groups before and after the treatment session. A: HMA group before treatment; B: HMA group after treatment; C: MESA group before treatment; D: MESA group after treatment; E: Bar graphs of the expression of protein zonula occludens-1, occludin and claudin-1 in HMA group and MESA group before and after the treatment session. HMA: Herb-partitioned moxibustion combined with acupuncture group; MESA: Mesalazine group; ZO-1: Zonula occludens-1.

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Figure 4 Expression of zonula occludens-1 mRNA, occludin mRNA and claudin-1 mRNA in two groups before and after the treatment session. A: HMA group before treatment; B: HMA group after treatment; C: MESA group before treatment; D: MESA group after treatment; E: Bar graphs of the expression of zonula occludens-1 mRNA, occludin mRNA and claudin-1 mRNA in HMA group and MESA group before and after the treatment session. HMA: Herb-partitioned moxibustion combined with acupuncture group; MESA: Mesalazine group; ZO-1: Zonula occludens-1.

Citation: Shang HX, Wang AQ, Bao CH, Wu HG, Chen WF, Wu LY, Ji R, Zhao JM, Shi Y. Moxibustion combined with acupuncture increases tight junction protein expression in Crohn’s disease patients. World J Gastroenterol 2015; 21(16): 4986-4996
URL: https://www.wjgnet.com/1007-9327/full/v21/i16/4986.htm
DOI: https://dx.doi.org/10.3748/wjg.v21.i16.4986