Genetic variations in colorectal cancer risk and clinical outcome

doi:10.3748/wjg.v20.i15.4167

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 21, 2014; 20(15): 4167-4177
Published online Apr 21, 2014. doi: 10.3748/wjg.v20.i15.4167

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Figure 1 Major pathways with significant genetic variants implicated in the development of colorectal cancer. Several pathways and related genes involved in the progression of colorectal cancer are illustrated. Genes with significant single nucleotide polymorphisms that are associated with colorectal cancer risk are represented with gray color. TGF-β: Transforming growth factor-β; BMP: Bone morphogenetic protein; CIMP: CpG island methylator phenotype; MSI: Microsatellite instability; CIN: Chromosomal instability.

Citation: Zhang K, Civan J, Mukherjee S, Patel F, Yang H. Genetic variations in colorectal cancer risk and clinical outcome. World J Gastroenterol 2014; 20(15): 4167-4177
URL: https://www.wjgnet.com/1007-9327/full/v20/i15/4167.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i15.4167