Effectiveness of interferon-gamma release assays for differentiating intestinal tuberculosis from Crohn’s disease: A meta-analysis

Figure 1 Flowchart of study selection.

Figure 2 Forest plot of estimates of sensitivity and specificity for interferon-gamma release assays in the differential diagnosis of intestinal tuberculosis from Crohn’s disease. Forest plot shows sensitivity and specificity of interferon-gamma release assays for intestinal tuberculosis diagnosis. The point estimates of sensitivity and specificity from each study are shown as solid circles. Error bars indicated 95%CI. Numbers indicate the studies included in the meta-analysis, as cited in the reference list. Pooled estimates for interferon-gamma release assays were as follows: sensitivity, 0.74 (95%CI: 0.68-0.80) and specificity, 0.87 (95%CI: 0.82-0.90).

Figure 3 Summary receiver operating characteristic curves for interferon-gamma release assays. Solid circles represent each study included in the meta-analysis. The size of each study is indicated by the size of the solid circle. Summary receiver operating characteristic (SROC) curves summarize the overall diagnostic accuracy.