Diabetic neuropathy: An evaluation of the use of quercetin in the cecum of rats

Figure 1 Representative micrographs showing immunoreactivity to general (green) and nitrergic (red) in the myenteric plexus of the rat cecum: A-C: Control group; D-F: Quercetin supplemented control group; G-I: Diabetic group; J-L: Quercetin supplemented diabetic group. Scale bar = 50 μm. nNOS: Neuronal nitric oxide synthase.

Figure 2 Representative micrographs showing immunoreactivity to HuC/D (green) and S-100 (red) in the myenteric plexus of the rat cecum. A-C: Control group; D-F: Quercetin supplemented control group; G-I, Diabetic group; J-L: Quercetin supplemented diabetic group. White arrows indicate glial cells present in nerve fibers. Scale bar = 50 μm.

Figure 3 Representative micrographs showing immunoreactivity to vasoactive intestinal peptide in the myenteric plexus of the rat cecum. A: Control group; B: Quercetin supplemented control group; C: Diabetic group; D: Quercetin supplemented diabetic group. Magnified inserts show varicosities of the individual nerve fibers. Note the enlarged appearance of the varicosities in the diabetic group (C) and the reduced varicosities in the quercetin diabetic group (D) compared with the controls (A and B). Scale bars = 50 μm for main panels, 15 μm for inserts.