Epstein-Barr virus negative primary hepatic leiomyoma: Case report and literature review

Figure 1 Abdominal computed tomography scan shows a mass in segment III of the liver. A: Hepatic equilibrium phase; B: Portal venous phase; C: Hepatic arterial phase. The arrows indicate the tumor in the liver.

Figure 2 Pathological characteristics of the primary liver leiomyoma. A: Tumor (arrow) located in segment III of the liver; B: Tumor (arrow) and normal liver tissue, hematoxylin and eosin staining, × 200; C: α-smooth muscle actin staining (arrow) of tumor tissues, immunohistochemical staining, × 200; D: Desmin staining (arrow) of tumor tissues, immunohistochemical staining, × 200.

Figure 3 Tumor cells stained negative by in situ hybridization with Epstein-Barr virus-encoded small RNA. A: Positive control staining × 200, × 1000; B: Tumor cell staining × 200, × 1000. Arrows indicate positive staining of the nuclei.