New reduced volume preparation regimen in colon capsule endoscopy

Figure 1 Reference used to evaluate the quality of bowel preparation prior to capsule ingestion. Experienced medical staff assessed the quality of the bowel preparation by checking the clarity of subjects’ evacuation before the subjects were given the colon capsule. We define that the capsule is ready to be ingested when a grade 5 quality is achieved.

Figure 2 Example of the contribution of dimethicone to improved mucosal visualization by the colon capsule. A: A lesion (arrow) is clearly observed on the transverse colon by colon capsule endoscopy. Dimethicone worked to join numerous microbubbles to form groups of large bubbles, resulting in better mucosal visualization; B: Colonoscopy image of the lesion post-capsule procedure. The lesion was diagnosed as a laterally spreading tumor. Endoscopic submucosal dissection was performed, and intramucosal cancer consisting of well differentiated adenocarcinoma was identified on the resected specimen.