Relationship between COX-2 and cell cycle-regulatory proteins in patients with esophageal squamous cell carcinoma

doi:10.3748/wjg.v16.i47.5975

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 21, 2010; 16(47): 5975-5981
Published online Dec 21, 2010. doi: 10.3748/wjg.v16.i47.5975

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Figure 1 Expression of cyclooxygenase-2 in normal esophageal mucosa and esophageal squamous cell carcinoma. Positive staining in cytoplasm in normal mucosa (A), well-differentiated squamous cell carcinoma (SCC) (B) and poorly-differentiated SCC (C). Counterstaining with hematoxylin, × 200.

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Figure 2 Expression of Ki-67 in normal esophageal mucosa and esophageal squamous cell carcinoma. Positive nuclei staining in normal esophageal mucosa (A, × 100), well-differentiated (B, × 200) and poorly-differentiated squamous cell carcinoma (C, × 200). Counterstaining with hematoxylin.

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Figure 3 Expression of cyclin A in normal esophageal mucosa and esophageal squamous cell carcinoma. Positive nuclei staining in normal esophageal mucosa (A, × 100), well-differentiated (B, × 200) and poorly-differentiated squamous cell carcinoma (C, × 200). Counterstaining with hematoxylin.

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Figure 4 Expression of p27 in normal esophageal mucosa and esophageal squamous cell carcinoma. Sections stained with anti-p27 antibody showing nuclear staining (brown) in normal esophageal mucosa (A, × 100), well-differentiated (B, × 200) and poorly-differentiated squamous cell carcinoma (C, × 200). Counterstaining with hematoxylin.

Citation: Huang JX, Xiao W, Chen WC, Lin MS, Song ZX, Chen P, Zhang YL, Li FY, Qian RY, Salminen E. Relationship between COX-2 and cell cycle-regulatory proteins in patients with esophageal squamous cell carcinoma. World J Gastroenterol 2010; 16(47): 5975-5981
URL: https://www.wjgnet.com/1007-9327/full/v16/i47/5975.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i47.5975