Epithelioid angiomyolipoma of the liver: Cross-sectional imaging findings of 10 immunohistochemically-verified cases

Figure 1 33-year-old woman with epithelioid angiomyolipoma in left lobe of liver (patient 7). A: Non-enhanced CT scan shows hypoattenuating lesion with fat components (arrow, CT value mean-35 Hu) in segments II/III/IV; B: Contrast-enhanced CT scan shows inhomogeneous enhancement lesion with punctiform or filiform enhanced vessels (arrowheads, the window width and level was adjusted) on arterial phase; C: Contrast-enhanced CT scan at 1-year follow-up shows enhanced recurrent nodule (arrow) on arterial phase image after the left lobe surgery.

Figure 2 55-year-old woman with epithelioid angiomyolipoma in left lobe of liver (patient 6). A: Non-enhanced CT scan shows hypoattenuating lesion in segment II; B: contrast-enhanced CT scan shows obviously enhanced lesion on arterial phase; C: the punctate enhanced vessels (arrowhead) within the lesion is show on an arterial phase image by adjusting the window width and level.

Figure 3 17-year-old girl with epithelioid angiomyolipoma in right lobe of liver (the patient had a history of tuberous sclerosis complex, patient 5). A: Non-enhanced CT scan shows homogeneous hypoattenuating lesion in segment V/VII/VIII; B: Contrast-enhanced CT scan shows inhomogeneous enhanced lesion with opacification of central vessels (arrow) on the arterial phase; C: The slight enhanced outer rim (arrow) around the inhomogeneous enhancement lesions is shown on portal phase contrast-enhanced CT; D: Immunohistochemical staining for HMB-45 shows diffusely positive staining in tumor cells within the cytoplasm (EnVision, × 100).

Figure 4 46-year-old woman with epithelioid angiomyolipoma in left lobe of liver (patient 9). A: Non-enhanced MRI T2WI shows hyperintense lesion in segment II/III; B: Contrast-enhanced MRI shows obvious enhanced lesions with outer rim enhancement (arrow) and opacification of punctate or curved vessels (arrowhead) on arterial phase.