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©2009 The WJG Press and Baishideng.
World J Gastroenterol. Jun 21, 2009; 15(23): 2855-2861
Published online Jun 21, 2009. doi: 10.3748/wjg.15.2855
Published online Jun 21, 2009. doi: 10.3748/wjg.15.2855
Figure 1 H pylori induces MIF and IL-8 production by injecting CagA into GECs via a type IV secretion system.
Figure 2 H pylori binds to CD74 on gastric epithelial cells and induces Nf-κB and Erk1/2 activation and IL-8 production.
Figure 3 IL-8 produced by epithelial cells binds to CXCR1 and CXCR2 and up-regulates CD74 expression in an autocrine manner.
- Citation: Beswick EJ, Reyes VE. CD74 in antigen presentation, inflammation, and cancers of the gastrointestinal tract. World J Gastroenterol 2009; 15(23): 2855-2861
- URL: https://www.wjgnet.com/1007-9327/full/v15/i23/2855.htm
- DOI: https://dx.doi.org/10.3748/wjg.15.2855