Adult T-cell leukemia/lymphoma presenting multiple lymphomatous polyposis

Figure 1 Colonoscopic images of the transverse colon. A: Multiple small polypoid lesions were presented; B: Closer observation revealed tiny submucosal tumors as well as whitish polypoid lesions.

Figure 2 Colonoscopic images with indigo carmine dye. A: Multiple lymphomatous polyposis was clearly depicted; B: Closer observation revealed polypoid and aphthoid lesions had tiny central depression.

Figure 3 Pedunculated colonic mucosal tissue. Biopsy specimens of the polypoid lesion showing diffuse proliferation of atypical lymphoid cells in the mucosal layer (A, HE, × 100). The lymphoma cells display pleomorphic nuclei and pale cytoplasm. (B, HE, × 400).

Figure 4 Immunohistochemical studies. The lymphoma cells were positive for CD3 (A, × 400), CD25 (B, × 400) and CD30 (C, × 400), consistent with ATLL, anaplastic large cell variant.