Novel mutations and sequence variants in exons 3-9 of human T Cell Factor-4 gene in sporadic rectal cancer patients stratified by microsatellite instability

Figure 1 Sequencing analysis of mutated hTCF-4 exon 4. Sequence chromatograms at the beginning of the exon 4: mutation 1 (391insA, 392 G > A, 393 A > G and 395delC) representing an amino acid change of Q131T and S132I and mutation 2 (395delC) altering reading frame and stopping after incorporating 22 amino acid. The arrow indicates the location of changes.