Relationship of quantitative structure and pharmacokinetics in fluoroquinolone antibacterials

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May 7, 2007 (publication date) through Apr 19, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. May 7, 2007; 13(17): 2496-2503
Published online May 7, 2007. doi: 10.3748/wjg.v13.i17.2496

Figure 1 The matrix of all fluoroquinolone antibacterials.

Figure 2 The substituents of fluoroquinolone antibacterials.

Figure 3 The alignment of fluoroquinolone molecules.

Figure 4 The comparison of the predicted and observed ln(AUC) (A) and ln(t_1/2) (B).

Citation: Cheng D, Xu WR, Liu CX. Relationship of quantitative structure and pharmacokinetics in fluoroquinolone antibacterials. World J Gastroenterol 2007; 13(17): 2496-2503
URL: https://www.wjgnet.com/1007-9327/full/v13/i17/2496.htm
DOI: https://dx.doi.org/10.3748/wjg.v13.i17.2496