Signal transduction of bombesin-induced circular smooth muscle cell contraction in cat esophagus

Figure 1 Inhibition of bombesin induced-contraction in permeabilized esophageal circular muscle cells by antibodies to G protein isoforms (Mean ± SE, Student’s t test, ^aP < 0. 05 vs Control).

Figure 2 Inhibition of bombesin-induced contraction in permeabilized esophageal circular muscle cells by antibodies to PLC isoforms (Mean ± SE, Student’s t test, ^aP < 0. 05 vs Control).

Figure 3 Contractile response of smooth muscle cells from cat esophagus to bombesin in presence of protein kinase C inhibitors (mean ± SE, n = 4, Student’s t test, ^bP < 0. 01 vs Control).

Figure 4 Effect of MEK inhibitor, PD98059 and p38 MAP kinase inhibitor, SB202190 on the bombesin-induced cat esophageal smooth muscle cell contraction (mean ± SE, n =  4).