Effective inhibition of expression of hepatitis B virus genes by DNAzymes

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Jun 21, 2005 (publication date) through Apr 25, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Viral Hepatitis

World J Gastroenterol. Jun 21, 2005; 11(23): 3504-3507
Published online Jun 21, 2005. doi: 10.3748/wjg.v11.i23.3504

Figure 1 Recognizing and catalytic sequences of DrzBS (A) and DrzBC (B) and their corresponding cleaving sites.

Figure 2 Dose-dependent inhibition of DNAzymes on the expression of HBsAg and HBeAg 48 h after administration of DrzBS or DrzBC.

Figure 3 Time-efficiency characteristics of DrzBS (A) and DrzBC (B) on the expressions of HBsAg and HBeAg.

Citation: Wo JE, Wu XL, Zhou LF, Yao HP, Chen LW, Dennin RH. Effective inhibition of expression of hepatitis B virus genes by DNAzymes. World J Gastroenterol 2005; 11(23): 3504-3507
URL: https://www.wjgnet.com/1007-9327/full/v11/i23/3504.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i23.3504