Specific COX-2 inhibitor NS398 induces apoptosis in human liver cancer cell line HepG2 through BCL-2

doi:10.3748/wjg.v11.i2.204

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Jan 14, 2005 (publication date) through Apr 19, 2024

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Times Cited (17)

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Liver Cancer

World J Gastroenterol. Jan 14, 2005; 11(2): 204-207
Published online Jan 14, 2005. doi: 10.3748/wjg.v11.i2.204

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Figure 1 Inhibition of HepG2 cell proliferation by NS-398.

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Figure 2 G0/G1 arrest and apoptosis of HepG2 cells induced by NS-398. A: G0/G1 arrest in HepG2 cells after treated with NS-398 for 72 h; B: Typical signs of programmed cell death after treated with NS-398.

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Figure 3 Inhibition of Bcl-2 mRNA (A) and Bcl-2 protein expression by NS-398 (B).

Citation: Huang DS, Shen KZ, Wei JF, Liang TB, Zheng SS, Xie HY. Specific COX-2 inhibitor NS398 induces apoptosis in human liver cancer cell line HepG2 through BCL-2. World J Gastroenterol 2005; 11(2): 204-207
URL: https://www.wjgnet.com/1007-9327/full/v11/i2/204.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i2.204