Effects of pharmacological serum from normal and liver fibrotic rats on HSCs

Figure 1 Liver fibrosis with inflammation necrosis and ballooning after CCl₄ injection for 9 wk (Masson, 100×).

Figure 2 HSCs in the media of different sera (immunocytochemistry stain of α-SMA, 400×). A: HSCs in NCS/RPMI-1640, B: HSCs in drug sera/RPMI-1640: cells expanded and synapses became fewer and smaller.

Figure 3 Immunocytochemistry stain of α-SMA in HSCs-positive cells: brown in plasm. When HSCs were inhibited, the number of HSCs decreased, while the expression of α-SMA increased, with cell bodies expanded and synapses fewer and smaller (200×). A: HSCs in normal serum of Salvia miltiorrhiza; B: HSCs in normal serum of Yigankang; C: HSCs in normal serum of colchicines; D: HSCs in normal serum of rats; E: HSCs in pathological serum of Salvia miltiorrhiza; F: HSCs in pathological serum of Yigankang; G: HSCs in pathological serum of colchicines; H: HSCs in pathological serum of fibrotic rats.