Molecular physiology of vesicular glutamate transporters in the digestive system

Figure 1 Predicted secondary structure of VGLUTs. Primary amino acid sequence and predicted secondary structure of rat VGLUT1 (GenBank accession number NM053859), mouse VGLUT2 (GenBank accession number AF324864), and mouse VGLUT3 (GenBank accession number NM182959). Eight putative transmembrane domains (TMDI–VIII) are indicated. Letter circle indicates amino acids conserved among all three members.

Figure 2 Phylogenic tree of VGLUTs superfamily. Dendrogram showing the relationship among rat VGLUT1 (GenBank accession number NM053859), mouse VGLUT2 (AF324864), mouse VGLUT3 (NM182959), C. elegans EAT-4 (AF095787), human sialin (AJ387747), and rabbit NPT1 (NM005074).