Effects of mifepristone on proliferation of human gastric adenocarcinoma cell line SGC-7901 in vitro

Figure 1 In situ hybridization (ISH) analysis of progesterone receptor (PR) expression in human gastric adenocarcinoma cell line SGC7901 (ISH, × 1000).

Figure 2 Transmission electron microscopic photographs of the SGC7901 cells cultured for 96 h in the absence (A) or the presence of 20 μmol/L mifepristone (B) in vitro (TEM, × 2000). Arrows indicate apoptotic bodies which were formed in the cells of mifepristone-treated group.

Figure 3 Effect of various concentrations of mifepristone on the ³H-TdR incorporation of SGC7901 cells at various time intervals in vitro.

Figure 4 RT-PCR analysis of Bcl-X_L mRNA expression in the SGC7901 cells cultured for 96 h in the absence or the presence of various concentrations of mifepristone in vitro. Lanes 1-5: Marker (bp), contro l, 5, 10, 20 μmol/L mifepristone, respectively.