Domperidone improves gallbladder emptying function in patients with irritable bowel syndrome

Figure 1 Gallbladder (GB) emptying after oral domperidone in 20 irritable bowel syndrome (IBS) patients after a meal stimulus. ● no drug, or ■ 10 mg Dom and ▲ 20 mg Dom. ^aP < 0.05, ^bP < 0.01, ^eP < 0.001, vs no Dom. GBEF: Gallbladder ejection fraction; Dom: Domperidone.

Figure 2 Effect of oral Domperidone on meal induced Gallbladder emptying in 18 controls. ● no Dom or ■ 10 mg Dom and ▲ 20 mg Dom. ^aP < 0.05, ^bP < 0.01, vs no Dom. GBEF: Gallbladder ejection fraction; Dom: Domperidone.