Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Gastroenterol. Jan 14, 2027; 33(2): 123953
Published online Jan 14, 2027. doi: 10.3748/wjg.123953
Published online Jan 14, 2027. doi: 10.3748/wjg.123953
Gastroduodenal arterioportal fistula: Two case reports and review of literature
Yun-Peng Zhang, Yu Lu, Hong-Zhen Wei, Ming Yang, Long He, Chuan-Bing Zhao, Zang-Long Deng, Jing-Jie Wang, Geng-Qiao Wang, He-Shui Wu, Tao Yin, Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430023, Hubei Province, China
Bin Liang, Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430023, Hubei Province, China
Co-first authors: Yun-Peng Zhang and Yu Lu.
Co-corresponding authors: He-Shui Wu and Tao Yin.
Author contributions: Zhang YP and Lu Y collected and analyzed the clinical data, reviewed the literature, and drafted the manuscript as co-first authors; Wei HZ, Yang M, He L, Zhao CB, Deng ZL, Wang JJ, and Wang GQ participated in the diagnosis and treatment of the patients, data collection, and patient follow-up; Liang B contributed to the interventional treatment and radiological evaluation and interpretation; Wu HS and Yin T jointly conceived and supervised the study, participated in the clinical management of the patients, and critically revised the manuscript; Wu HS and Yin T contributed equally as co-corresponding authors. All authors read and approved the final manuscript.
AI contribution statement: No AI tools were used during the preparation of this manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Tao Yin, Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan 430023, Hubei Province, China. ytwhun@hust.edu.cn
Received: June 2, 2026
Revised: July 21, 2026
Accepted: September 9, 2026
Published online: January 14, 2027
Processing time: 158 Days and 17.8 Hours
Revised: July 21, 2026
Accepted: September 9, 2026
Published online: January 14, 2027
Processing time: 158 Days and 17.8 Hours
Core Tip
Core Tip: Gastroduodenal arterioportal fistula is an exceedingly rare vascular malformation with non-specific symptoms. Through two contrasting cases, we highlight that treatment should be individualized by fistula anatomy and coexisting solid-organ pathology rather than a rigid “intervention-first” rule. Anatomically simple lesions with an accessible draining vein are curable by combined transarterial and transportal embolization, whereas complex, multi-fed fistulas with pancreatic arteriovenous malformation warrant upfront pancreaticoduodenectomy.