Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Gastroenterol. Oct 28, 2026; 32(40): 120622
Published online Oct 28, 2026. doi: 10.3748/wjg.120622
Published online Oct 28, 2026. doi: 10.3748/wjg.120622
Esophageal diverticulum: A clinical framework for patient-tailored endoscopic management
Xin-Ran Song, School of Clinical Medicine, Capital Medical University, Beijing 100069, China
Yu-Xi Liu, School of Clinical Medicine, Beijing Luhe Hospital Affiliated to Capital Medical University, Beijing 101149, China
Xiao-Feng Wu, Ran Xue, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Early Drug Development Center, Peking University Cancer Hospital & Institute, Beijing 100142, China
Ran Xue, Department of Gastroenterology, Beijing Chao‑Yang Hospital, Capital Medical University, Beijing, 100020, China
Co-first authors: Xin-Ran Song and Yu-Xi Liu.
Author contributions: Xue R conceived and designed the paper; Song XR, Liu YX, and Wu XF wrote the manuscript and analyzed the data. All authors read and approved the final manuscript. Song XR and Liu YX are co-first authors of this work. They contributed equally to the writing of the manuscript, data analysis, and interpretation of the results. Both authors participated in the revision of the manuscript and approved the final version. Their respective contributions are of equal importance and are inseparable in the completion of this study. Therefore, co-first authorship is fully justified.
AI contribution statement: DeepSeek and GeenMedical were used during the preparation of this manuscript. No portion of the main text (Abstract, Introduction, Materials and Methods, Results, Discussion, Conclusion) was directly generated by AI. The AI tool was only used for language refinement and grammar checking. AI tool was used for language polishing, translation and writing assistance. No AI tool was used for data analysis. AI did not participate in the study design or interpretation of results. No AI-generated images are included in this manuscript.
Supported by grants from Beijing Xisike Clinical Oncology Research Foundation, No. Y-SY2024QN-0110; and Science Foundation of Peking University Cancer Hospital, No. BJCH2026GG03.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Corresponding author: Ran Xue, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Early Drug Development Center, Peking University Cancer Hospital & Institute, No. 52 Fucheng Road, Haidian District, Beijing 100142, China. xueran2@sina.com
Received: March 4, 2026
Revised: April 15, 2026
Accepted: May 27, 2026
Published online: October 28, 2026
Processing time: 191 Days and 2.6 Hours
Revised: April 15, 2026
Accepted: May 27, 2026
Published online: October 28, 2026
Processing time: 191 Days and 2.6 Hours
Core Tip
Core Tip: This review establishes a comprehensive decision-making framework for the endoscopic treatment of esophageal diverticula, encompassing the multi-dimensional preoperative assessment of patients, precise selection of techniques and devices, and dual evaluation of postoperative outcomes. The core perspective lies in emphasizing the formulation of individualized strategies based on diverticulum characteristics and patient conditions, assisting in achieving precision medicine in clinical practice.