Zeng Y, Zhang JW, Yang J. Endoscopic management of infected necrotizing pancreatitis: Advancing through standardization. World J Gastroenterol 2025; 31(20): 107451 [DOI: 10.3748/wjg.v31.i20.107451]
Corresponding Author of This Article
Jian Yang, MD, PhD, Associate Chief Physician, Department of Gastroenterology, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, Chongqing 400016, China. yj1984ren@qq.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. May 28, 2025; 31(20): 107451 Published online May 28, 2025. doi: 10.3748/wjg.v31.i20.107451
Endoscopic management of infected necrotizing pancreatitis: Advancing through standardization
Yan Zeng, Jun-Wen Zhang, Jian Yang
Yan Zeng, Department of Psychology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China
Jun-Wen Zhang, Jian Yang, Department of Gastroenterology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
Author contributions: Zeng Y and Yang J performed the literature search, analyzed the data, and wrote the original manuscript; Zhang JW and Yang J performed the endoscopic procedures, conceptualized and designed the research, and edited the final manuscript; all authors have read and approved the final manuscript.
Supported by the Education and Teaching Reform Project of the First Clinical College of Chongqing Medical University, No. CMER202305; Natural Science Foundation of Tibet Autonomous Region, No. XZ2024ZR-ZY100(Z); and Program for Youth Innovation in Future Medicine, Chongqing Medical University, China, No. W0138.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jian Yang, MD, PhD, Associate Chief Physician, Department of Gastroenterology, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, Chongqing 400016, China. yj1984ren@qq.com
Received: March 24, 2025 Revised: April 12, 2025 Accepted: May 12, 2025 Published online: May 28, 2025 Processing time: 65 Days and 18.2 Hours
Core Tip
Core Tip: Endoscopic therapy serves as the first-line treatment for infected necrotizing pancreatitis (INP), effectively reducing mortality and complication rates. Standardizing INP endoscopic management relies on multidisciplinary collaboration, advanced imaging techniques (e.g., three-dimensional reconstruction, endoscopic ultrasound-guided procedures), and biomarker-driven strategies (C-reactive protein, procalcitonin) to tailor interventions, optimize timing, and minimize complications. Addressing the heterogeneity in endoscopic management remains crucial, requiring clarification of optimal intervention windows, selection of appropriate stents, implementation of combined therapies for complex lesions, and strategies to reduce endoscopic debridement sessions and complication risks, thereby guaranteeing individualized therapeutic demands with clinical efficacy assurance.
