Letter to the Editor
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. May 21, 2025; 31(19): 105888
Published online May 21, 2025. doi: 10.3748/wjg.v31.i19.105888
Characterization of subepithelial tumors of upper gastrointestinal tract by endoscopic ultrasound
Santosh Shenoy
Santosh Shenoy, Department of General Surgery, Kansas City VA Medical Center, University of Missouri, Kansas City, MO 64128, United States
Author contributions: Shenoy S designed the overall concept and outline of the manuscript and the writing, discussion, editing the manuscript, and review of literature.
Conflict-of-interest statement: The author reports no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Santosh Shenoy, MD, FACS, Professor, Department of General Surgery, Kansas City VA Medical Center, University of Missouri, 4801 E Linwood, Kansas City, MO 64128, United States. shenoy2009@hotmail.com
Received: February 11, 2025
Revised: March 5, 2025
Accepted: March 21, 2025
Published online: May 21, 2025
Processing time: 101 Days and 1.2 Hours
Core Tip

Core Tip: Esophageal gastrointestinal stromal tumor (GIST) is a rare type of mesenchymal tumor. Esophageal GISTs account for < 1% of all GISTs. Endoscopic resection remains the mainstay for small, localized tumors with excellent outcomes. Endoscopic ultrasound (EUS) is a crucial tool in the diagnosis, staging, and management of esophageal GIST. Given the submucosal nature of these tumors, standard endoscopy is not adequate, making EUS essential for a comprehensive assessment. EUS provides accurate tumor sizing, and enables fine needle aspiration guided biopsy of carefully selected large inoperable tumors or where diagnosis is in doubt, which is critical for risk stratification and treatment planning.