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Liu J, Liu YL. Should we pay more attention to the potential link between Helicobacter pylori and esophageal cancer in Asian countries. World J Gastroenterol 2024; 30(46): 4958-4963 [PMID: 39679315 DOI: 10.3748/wjg.v30.i46.4958]
World J Gastroenterol. Dec 14, 2024; 30(46): 4958-4963 Published online Dec 14, 2024. doi: 10.3748/wjg.v30.i46.4958
Should we pay more attention to the potential link between Helicobacter pylori and esophageal cancer in Asian countries
Jie Liu, Ying-Ling Liu
Jie Liu, Ying-Ling Liu, Department of Gastroenterology, The First Affiliated Hospital of University of Science and Technology of China, Hefei 230001, Anhui Province, China
Author contributions: Liu J contributed to draft of the manuscript; Liu YL contributed to critical revision of the manuscript; all of the authors read and approved the final version of the manuscript to be published.
Supported by Research Project of the Chinese Digestive Early Cancer Physicians' Joint Growth Program, No. GTCZ-2021-AH-34-0012; and Lu'an Science and Technology Plan Project, No. 2022lakj040.
Conflict-of-interest statement: All authors declare no conflict of interest in publishing the manuscript.
Corresponding author: Ying-Ling Liu, MD, Associate Chief Physician, Department of Gastroenterology, The First Affiliated Hospital of University of Science and Technology of China, No. 9 Lujiang Road, Hefei 230001, Anhui Province, China. liuyingling@ustc.edu.cn
Received: July 23, 2024 Revised: October 25, 2024 Accepted: November 1, 2024 Published online: December 14, 2024 Processing time: 120 Days and 15.3 Hours
Core Tip
Core Tip: Helicobacter pylori (H. pylori) has been implicated in the development of gastric cancer and its eradication is widely accepted as a treatment approach. However, recent research indicates that H. pylori may also play a role in maintaining the balance of gastroesophageal junction cells and could potentially have a protective effect against esophageal cancer (EC). Previous meta-analyses have shown that the relationship between H. pylori and the risk of esophageal squamous cell carcinoma or esophageal adenocarcinoma varies across different regions. This manuscript discusses a recent study by López-Gómez et al. Additionally, an updated meta-analysis focusing on the potential link between H. pylori and EC in Asian populations has been conducted to offer more precise clinical recommendations for countries like China and other Asian nations.
